Miocic won the belt at UFC 198, defeating Fabricio Werdum. He will be defending in his hometown with the UFC visiting Cleveland for the first time.
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Overeem is currently riding a 4-fight win streak. His last win was a TKO win over Andrei Arlovski at UFC Fight Night 87.
UFC 203 takes place September 10th at the Quicken Loans Arena in Cleveland.
More matches are expected to be announced.