“The Eagle,” 29, has been plagued with injuries and weight-cutting issues, with his last fight in the octagon a dominant submission win over Michael Johnson at UFC 205 in November 2016.
Barboza, 31, has rebounded from a loss to Tony Ferguson with three consecutive victories.
UFC 219 is scheduled for Dec. 30 at the T-Mobile Arena in Las Vegas. The current card includes:
Khabib Nurmagomedov (24-0-0) vs. Edson Barboza (19-4-0)
Kamaru Usman (11-1-0) vs. Emil Weber Meek (9-2-1)
Cynthia Calvillo (6-0-0) vs. Carla Esparza (12-4-0)
Myles Jury (16-2-0) vs. Rick Glenn (20-4-1)
Dominick Cruz (22-2-0) vs. Jimmie Rivera (21-1-0)
Carlos Condit (30-10-0) vs. Neil Magny (18-6-0)
Louis Smolka (11-4-0) vs. Matthew Nicolau (12-1-1)
Gokhan Saki (1-1-0) vs. Khalil Rountree (6-2-0)