The two were supposed to meet at UFC 223, but were scratched when Chiesa was injured by broken glass during the fighter bus melee.
Chiesa had a three fight win streak snapped by a submission loss to Kevin Lee at UFC Fight Night 112 in June 2017.
— Michael Chiesa (@MikeMav22) May 1, 2018
Pettis was submitted by Dustin Poirier at UFC Fight Night 120 in November 2017.
UFC 226 is scheduled for July 7 at the T-Mobile Arena in Las Vegas. The current card includes:
Max Holloway (19-3-0) vs. Brian Ortega (14-0-0)
Francis Ngannou (11-2-0) vs. Derrick Lewis (19-5-0)
Michael Chiesa (14-3-0) vs. Anthony Pettis (20-7-0)
Raphael Assuncao (26-5-0) vs. Rob Font (15-3-0)
Gokhan Saki (1-1-0) vs. Khalil Rountree (6-3-0)
Mike Perry (11-3-0) vs. Yancy Medeiros (15-5-0)
Paulo Henrique Costa (11-0-0) vs. Uriah Hall (13-8-0)
More bouts are expected to be announced.