Cirkunov, 31, who immigrated to Canada from Latvia at 12 years old, recently snapped a two fight losing skid with a submission win over Patrick Cummins at UFC Fight Night 138 in October 2018.
Meanwhile, St. Preux, 35, a former American Tennessee college gridiron star, has struggled as of late, losing two of his last three fights, including a decision loss to Dominick Reyes in his last bout at UFC 229 in October 2018.
UFC 235 is scheduled to take place March 2 at the T-Mobile Arena in Las Vegas. Current bouts include:
Ovince St. Preux (23-12-0) vs. Misha Cirkunov (14-4-0)
Tyron Woodley (19-3-1) vs. Kamaru Usman (14-1-0)
Ben Askren (18-0-0) vs. Robbie Lawler (28-12-0)
Nick Diaz (26-9-0, 2NC) vs. Jorge Masvidal (32-13-0)
Macy Chiasson (3-0-0) vs. Gina Mazany (5-2-0)
Jeremy Stephens (28-15-0) vs. Zabit Magomedsharipov (16-1-0)
Tecia Torres (10-3-0) vs. Weili Zhang (18-1-0)
Mickey Gall (5-1-0) vs. Diego Sanchez (28-11-0)
More bouts are expected to be announced.